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Zofran (Ondansetron)

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What kind of drug is Zofran (ondansetron)?

Zofran is a medicine used for the treatment of nausea and vomiting resulting from radiation or chemotherapy treatments for cancer. Its effects are based on blocking the activity of chemicals responsible for causing nausea and vomiting. There may be certain other purposes for ondansetron use, but you will have to discuss those with your health care provider before you start Zofran treatment. You are not supposed to be taking ondansetron if you are allergic to dolasetron, palonosetron, ondansetron, or granisetron.

Before you can start Zofran (ondansetron) treatment

Talking to your health care provider before starting to use ondansetron is very important, as you will be able to avoid unpleasant reactions of your body to the treatment. Your health care provider will be interested to know if you have or used to have liver disease or a personal history of Long QT syndrome. Also, tell your health care provider if there was a family history of Long QT syndrome, because this factor can affect your treatment and the dose of the medicine you are prescribed.

How you need to use Zofran (ondansetron)

You will need to take Zofran exactly as your doctor prescribed, even if those instructions are slightly different from those on the label of your medicine. You will usually be taking ondansetron with a full glass of water, as well as some food (optional). It's best that you take Zofran in the same way every time. This means that if you take ondansetron with some food, make sure you take it that way every time for your body to get accustomed to the routine better. If you have been prescribed the orally disintegrating tablet of Zofran, make sure you use dry hands to remove the tablet from the blister and place into you mouth. You need to swallow several times after that to make sure the dose of Zofran you were supposed to take reaches your stomach sooner and starts acting. The liquid form of ondansetron must be taken with the help of a special measuring device.

Can I take other drugs apart from Zofran (ondansetron)?

You may be able to take other medications besides Zofran, but your doctor will have to be aware of that and approve it before you do. You will have to report any medications you are already using, as well as the ones you are planning to use. The following ones are crucial to report to your health care provider before you start taking ondansetron: carbamazepine, phenobarbital, rifampin, tramadol, or phenytoin. If there are any other drugs you think your doctor needs to know about, do not hesitate to report those as well, because the list above gives only the names of most common medications known to interact with Zofran.

FDA category for Zofran (ondansetron)

Zofran has been classified as FDA pregnancy category B. This category is used for drugs that are not expected to harm an unborn child no matter which trimester they are taken during. However, you will still have to report the fact of being pregnant or breastfeeding to your doctor to see if any other medications you may need to combine with ondansetron are possible to take. There is not enough information on the effects Zofran may have when you breastfeed a child, but there is a chance it may pass into your breast milk. You should not take Zofran if you are breastfeeding a baby without first talking to your health care provider about it.

If you take too much of Zofran (ondansetron)

If you happened to take too much of ondansetron for any reason, make sure you seek emergency medical assistance and report any overdose symptoms you developed. You will have to keep the following ones in mind and report them in such cases: light-headedness, severe constipation, fainting or sudden loss of vision. Other symptoms of Zofran overdose are also possible because different people may have different reactions to too much of ondansetron.

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